Globulins in Kala-Azar
نویسنده
چکیده
distilled water it becomes cloudy owing to partial precipitation of the serum globulin. Under certain circumstances, a copious precipitate forms instead of a mere cloudiness. This precipitate is due to a globulin-like substance as is evident from the following facts:? (1) It is soluble in normal saline, in dilute acids, and in dilute soda bicarb, solution. It is also soluble in sodium hydrate solution. (2) It is precipitated from its solution in normal saline when the solution is treated with equal parts of a saturated solution of (NH4)2 S04 or when it is saturated with MgS04 or IVaCl. (3) It is not precipitated by jNtH4OH from its solution in dilute acids. (4) It is insoluble in distilled water. On chemical analysis, this substance is found to contain C, ]ST, H, 0, but so far I have not
منابع مشابه
Smouldering focus of kala-azar in Assam.
Sir, Kala-azar, transmitted by sandflies was endemic in Assam until 1950, with three major epidemics between 1875 and 19501,2. Intensive insecticide spraying as part of National Malaria Eradication Programme eliminated the disease from Assam by mid 1950s, except for isolated case reports upto 19853. We recently diagnosed kalaazar in an adult male aged 43 years from Guwahati city, Assam, who was...
متن کاملImpact of amphotericin-B in the treatment of kala-azar on the incidence of PKDL in Bihar, India.
BACKGROUND & OBJECTIVE Of the two reservoirs of infection of kala-azar i.e., patients of kala-azar and post kala-azar dermal leishmaniasis (PKDL), PKDL provides easy access for the sandfly to pick up the parasites. In the last epidemic of 1977 in India, the importance of PKDL as a potential cause of increase in number of kala-azar cases was ignored. During recent years, we found an increase in ...
متن کاملDNA polymorphism assay distinguishes isolates of Leishmania donovani that cause kala-azar from those that cause post-kala-azar dermal Leishmaniasis in humans.
Leishmania donovani in India causes visceral infection (kala-azar) and dermal infection (post-kala-azar dermal leishmaniasis). We report here the identification of polymorphism in a well-defined genetic locus among the Leishmania parasites causing the visceral and dermal manifestations, in a comparison of 15 post-kala-azar dermal leishmaniasis and 12 kala-azar patient isolates.
متن کاملSpatial and temporal variation and hotspot detection of kala-azar disease in Vaishali district (Bihar), India
BACKGROUND An improved understanding in transmission variation of kala-azar is fundamental to conduct surveillance and implementing disease prevention strategies. This study investigated the spatio-temporal patterns and hotspot detection for reporting kala-azar cases in Vaishali district based on spatial statistical analysis. METHODS Epidemiological data from the study area during 2007-2011 w...
متن کاملPost-Kala-Azar Dermal Leishmaniasis in Mymensingh, Bangladesh
the patient had visceral leishmaniasis (kala-azar), successfully treated with 30 intramuscular injections of sodium stibogluconate (SSG). Polymerase chain reaction showed Leishmania donovani DNA in a buffy coat specimen. Post-kala-azar dermal leishmaniasis (PKDL) is a chronic skin rash usually seen in apparently cured kala-azar patients in East Africa and South Asia. In the Indian subcontinent,...
متن کاملSeptic Arthritis Caused by Streptococcus suis Serotype 5 in Pig Farmer
1. Rogers L. The epidemic malarial fever of Assam, or kala-azar, successfully eradicated from tea garden lines. Br Med J. 1898; 2:891–2. 2. Price JD, Rogers L. The uniform success of segregation measures in eradicating Kala-azar from Assam tea gardens: it is bearing on the probable mode of infection. BMJ. 1914;1:285–9. http://dx.doi. org/10.1136/bmj.1.2771.285 3. Kaul SM, Sharma RS, Borgohain B...
متن کامل